What effect may Isoflurane 1.7% induce during neurophysiologic monitoring?

Isoflurane at a concentration of 1.7% is known to have significant effects on the central nervous system during neurophysiologic monitoring. One of the notable effects of this anesthetic agent is its ability to induce burst suppression on the electroencephalogram (EEG). Burst suppression refers to periods of high amplitude electroencephalographic activity (bursts) followed by periods of significantly reduced or flat activity (suppression). This pattern suggests a significant depression of neuronal activity, which can occur at higher doses of volatile anesthetics like isoflurane.

In the context of intraoperative monitoring, observing burst suppression can play an important role in understanding the effects of anesthesia on brain function, especially during procedures that may put the brain at risk or require constant monitoring of its activity. This information can guide anesthetic management and ensure patient safety during surgery.

Nerve conduction velocity is generally decreased under the influence of isoflurane, rather than increased. Similarly, isoflurane does not enhance motor responses; instead, it may lead to a decrease in neuromuscular function through its depressant effects. While the anesthetic may help minimize patient movement due to sedation and muscle relaxation, this is more of a side effect than a primary